The quantity of bacilli from nasal mucosal lesions in lepromatous leprosy ranged from 10 thousand to 10 million (Shepard 1960).
The use of the word "leprosy" before the mid-nineteenth century, when microscopic examination of skin for medical diagnosis was first developed, can seldom be correlated reliably with Hansen's disease as we understand it today.
When the WHO declares that leprosy has been eliminated, according to their definition of 1/10,000, then in a world of 6 billion people that leaves 600,000 people with leprosy.
The majority of lepromatous patients showed leprosy bacilli in their nasal secretions (Pedley 1973), which produced as many as 10 million viable organisms per day (Davey et al.
The WHO determined that the duration of treatment for MB leprosy could be shortened safely to 12 months "without significantly compromising its efficacy."
In 1995, the World Health Organization (WHO) estimated that between two and three million individuals were permanently disabled because of leprosy (WHO 1995).
The crucial breakthrough in the cure for leprosy came when G. H. A. Hansen followed the lead of Robert Koch, who first suggested that microorganisms could cause disease.
The search for more effective anti-leprosy drugs led to the use of clofazimine and rifampicin in the 1960s and 1970s (Rees et al.
Patients with this chronic infectious disease are classified as having either: (1) paucibacillary (tuberculoid leprosy), (2) multibacillary Hansen's disease (lepromatous leprosy), or (3) borderline leprosy.
At the galactic location of the solar system, the escape velocity with regard to the gravity of the Milky Way is about 1,000 kilometers per second.
In 1985 UNESCO listed Petra as a World Heritage Site, describing it as "one of the most precious properties of man's cultural heritage."
The minimum winter temperature in Hanoi can dip as low as 6–7°C (43°F), not accounting for the wind chill factor, while summer can get as hot as 38–40 (100-104°F).
The word "leprosy" derives from the ancient Greek words lepros, a "scale," and lepein, "to peel" (Barnhart 1995).
Recently, leprosy has also emerged as a problem in HIV patients on antiretroviral drugs (McNeil Jr. 2006).
The Leprosy Mission of Canada estimates that 4 million people are currently suffering from leprosy (L.M.C.
Cochrane and used at the hospital compound in Carville, Louisiana in 1946, there was no effective cure for leprosy.
The clinical manifestations of leprosy vary but primarily affect the skin, nerves, and mucous membranes (Naafs et al.
Registered prevalence is a better indicator of the disease burden, since it reflects the number of active leprosy cases diagnosed and receiving treatment with M.D.T.
Aside from humans, other creatures that are known to be susceptible to leprosy include the armadillo, mangabey monkeys, rabbits, and mice.
The exact mechanism of transmission of leprosy is not known.
The mere mention of leprosy has struck fear in the hearts of people for thousands of years.
Fairly large numbers of M. leprae have been found in the superficial keratin layer of the skin of lepromatous leprosy patients, suggesting that the organism could exit along with sebaceous secretions (Job et al.
The successful transmission of leprosy through aerosols containing M. leprae in immune-suppressed mice suggests a similar possibility in humans (Rees et al.
A disease called "leprosy" was recorded in ancient India (fifteenth century B.C.E.
Leprosy or Hansen's disease is a chronic infectious disease caused by the bacterium Mycobacterium leprae and is the only known bacterium that infects peripheral nerves.
By the 1960s, the world’s only known anti-leprosy drug became virtually useless.
When Hansen began to look into the "invisible" world for the cause of leprosy, he risked everything he had in order to help those that no one else wanted to touch.
Table 2 shows the leprosy situation in the six major countries that have yet to achieve the goal of elimination at the national level.