How does chloroform knock people out?

To be honest, this medication is no longer taught in anesthesiology courses at the medical student level. The mechanism of action is through a receptor in brain called as GABA-A, which is a major suppressive neurotransmitters in brain. This recept... read more

Chloroform is well-known for its anesthetic properties. If consumed in mild doses, it can daze or knock out the recipient, whereas when consumed in high concentrations, it has the potential to kill the subject. read more

Chloroform “knocks you out” for as long as it is applied, this could be for 20 minutes to two hours with a 20–30 minute recovery time; during which there will be intense shivering, severe nausea and more than likely vomiting, then a severe headache lasting hours. Unless you're asking how long does it take to knock someone out with chloroform. read more

Yes, chloroform knocks people out. It was used as a medical anesthetic in the 19th century, but the anesthetic dose is close to the fatal dose, so people stuck with ether (diethyl ether). Chloroform is a liquid that boils at 61C, but it evaporates faster than water at room temperature. read more