Are opioids depressants?

Contrary to popular misconception, opioids are not depressants in the classical sense. [citation needed] They do produce central nervous system depression, however, they also excite certain areas of the central nervous system. To remain true to the term 'depressant' - opioids cannot be classified as such. read more

One “natural,” nonmedicinal use of opioids for depression is already widespread. There is a generally accepted hypothesis that long distance running produces a “runners’ high” via the production of endorphins, one of the brain’s opioids. Intense exercise is often “prescribed” for the treatment of depression. read more