Yes — although the term "full-blooded" is problematic. It seems to assume that "real" Cherokees are defined by having an entirely Cherokee lineage, without European, African, or even Native ancestors from a different tribe. read more
This is like asking if there are any"full blooded" Alsatians or Breton or Canadian or Englishman. And it is pretty creepy. Being"full blooded" is not any measure of who you are or what culture you belong to. read more
Full-blooded is often a relative term in as much that sometimes full-bloods are full-bloods of their own tribe. Sometimes full-bloods may be a mix of different nations. Half-Comanche and half-Kiowa, for instance, is a very common mix among my people. read more