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What causes sudden decrease in platelets in dengue?

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Our blood comprises of red blood cells, white blood cells, platelets and plasma. The function of platelets is to repair the vessels that puncture or tear, so that the blood does not 'leak out'. They do this by forming a mesh type structure over the damaged vessel and retain the blood to flow within the vessel itself. read more

The cause of decreased platelet count( thrombocytopaenia) is : When the body is infected with dengue virus it tries to fight the infection by producing antibodies. how ever the proteins on the dengue virus and human platelets is similar at the molecular level. read more

Slight decrease in the platelet count does not contribute to the disease but when it is below 50,000 per micro litre, thrombocytopenia occurs. Low platelet count in dengue fever can be very dangerous. The reasons for low platelet count in dengue fever are as follows. Dengue virus, the main cause of dengue fever induces bone marrow suppression. read more

Some patients experience the development of the condition into a life-threatening stage referred to as dengue-hemorrhagic fever, where bleeding, blood plasma leakage, and low platelet count takes place. The drop in platelet levels is a result of the attack brought about by the virus to the location where platelets are produced, the bone marrow. read more

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