Once the disease has advanced to Stage IV, melanoma cells have traveled through the body via the bloodstream or lymph vessels, going far from the original tumor site. They may have reached distant lymph nodes or invaded the internal organs. This can be in addition to or instead of in-transit metastases or local spread to the regional lymph nodes. read more
Very high. Neglected sqamous cell skin cancer is a very lethal lesion. It rapidly penetrates to deeper layers of skin, spread to regional lymph nodes. read more