Can people become high on antidepressants?

Some people feel a mood boost when they start Effexor, but it’s not really a high. It’s more of a not-low. People can become manic on ADs, which in some manifestations is like being high. Things can seem especially wonderful to them, and they might chatter on and on and on about how wonderful those things are. read more

Four out of 10 people treated with antidepressants improve with the first one they try. If the first antidepressant medication doesn’t help, the second or third often will. Most people eventually find one that works for them. read more