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Painful or damaging blockages are called sickle cell crises. They can be caused by a variety of circumstances, including: illness; changes in temperature; stress; poor hydration; altitude; The following are types of complications that can result from sickle cell anemia. Severe anemia. Anemia is a shortage of RBCs. Sickle cells are easily broken. read more
Sickle cell anemia can cause pains including joint stiffness, muscle weakness, bone pain and abdominal or chest pain. Using over-the-counter pain-killers often is not recommended because they can negatively affect kidney and/or liver function. read more
So, bacteria can reach the lung and cause inflammation of the lung tissue. This inflammation will reduce the oxygen supply and will create the shape of the red blood cells to become more sickle. More abnormality in the form of red blood cells will make it more easy for them to stick together to block the blood flow. read more