A well known side effect of Warfarin, mostly seen when overdosed making the blood too "thin" but occasionally when the blood thinning effect is within normal range is having a bleeding = hemorrage which can cause a painful swelling in the place where the bleeding is located, so also possible in the leg. read more
Warfarin is unlikely to cause leg swelling, especially if it is on only one side. However, the condition Warfarin is commonly given to PREVENT, blood clots, can cause swelling in one leg. If your doctor has prescribed Warfarin for you and you have swelling in your leg, you need to see your doctor without delay. read more
#90 in Warfarin discussions - 123 posts discuss Leg Swelling with Warfarin. Leg Swelling is #90 concern in Warfarin discussions. read more
Bleeding: Excessive bleeding is the danger of too much coumadin (warfarin). Bleeding into the skin can cause bruising and pain. Into muscle can cause a hematoma and stiffness and could lead to a compartment syndrome. Into a joint, can cause swelling, stiffness, and pain. read more