Yes. Graphic card memory and system memory have nothing to do with each other. You can use a GDDR5 graphics card on a motherboard that accepts only DDR3 system memory. Yes you should. read more
rolandzhang3 said: Yes, DDR3 is the RAM that your motherboard supports, GDDR5 is the VRAM that comes on the graphics card. The graphics card doesn't use your ram slot, it uses the PCI-Express slot. read more