Do hallucinogens cause residual neuropsychological toxicity?

... such as subjects' premorbid cognitive and personality function and prior use of other substances. At present, the literature tentatively suggests that there are few, if any, long-term neuropsychological deficits attributable to hallucinogen use. read more

John H. Halpern 1,a,*, Harrison G. Pope1 Jr. b a Alcohol and Drug Abuse Research Center, McLean Hospital, 115Mill Street, Belmont, MA 02478, USA read more

Returning to the clinical question of the neuropsychological toxicity of hallucinogen use, future studies should take care to address the various methodological problems reviewed above. A particular concern is the difficulty of securing a population of hallucinogen users who are free of concomitant psychopathology and/or other psychoactive drug use. read more

Hallucinogens generally possess relatively low physiological toxicity, and have not been shown to result in organ damage or neuropsychological deficits (Strassman, 1984; Gable, 1993, 2004; Halpern and Pope, 1999; Hasler, et al., 2004; Nichols, 2004; Halpern, et al., 2005). read more