Do hormones get destroyed by the gastric acid in the stomach?

Unsurprisingly, hormones are a large class of substances. How they react with acids depends on… the individual structure of the hormone in question. read more

In the case of peptide hormones, the acid won’t be the problem, but the peptide-cleaving enzymes in the stomach, which will reduce a peptide-hormone to its constituent bits. Which is why you cannot give TRH orally. read more

Pepsin works in a highly acidic environment, so when HCl is low, your stomach has difficulty processing your food. When this happens, your stomach may release more gastric acid (which is also called an acid rebound). This can also happen when you take an antacid like TUMS, which neutralize the acid. read more

Gastrin is a hormone that is produced by ‘G’ cells in the lining of the stomach and upper small intestine. During a meal, gastrin stimulates the stomach to release gastric acid. This allows the stomach to break down proteins swallowed as food and absorb certain vitamins. read more