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Do people build tolerance to supplemental melatonin?

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I doubt very much that anyone has ever studied the issue to give a certain answer to your question. But my suspicion would be no— because as a natural substance, melatonin is always present to SOME extent. Also, the effects of melatonin are subtle enough that 'tolerance' would be difficult to determine. read more

I doubt very much that anyone has ever studied the issue to give a certain answer to your question. But my suspicion would be no— because as a natural substance, melatonin is always present to SOME extent. read more

The amount that our bodies make is much smaller than the dosages of a typical over-the-counter melatonin supplement. So when a person takes a melatonin supplement, they are overwhelming their melatonin receptors, which causes a negative feedback loop. read more

Melatonin is not considered an effective treatment for insomnia. Melatonin in pill form does not function like your body’s naturally produced melatonin: It affects the brain in bursts and rapidly leaves the system, instead of the slow build-up and slow wash-out that your body’s naturally produced melatonin experiences. read more

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