Interesting question! As everyone else in this thread points out, yes, it definitely makes a difference The reason being the same as why vodka shots get you more drunk than beer- even though, both are basically the same chemically- ethanol. read more
The liver has a ceiling to the amount of alcohol it can metabolise per unit time. The value happens to be 0.015g/100ml/hour, on average. As you get better and better at drinking this clearance limit increases, with the liver producing more amount of enzymes for breaking down alcohol. read more