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Does melatonin stimulate the growth hormone (GH)?

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Melatonin stimulates growth hormone secretion through pathways other than the growth hormone-releasing hormone. Valcavi R(1), Zini M, Maestroni GJ, Conti A, ... The aim of this study was to investigate the neuroendocrine mechanisms by which melatonin modulates GH secretion. read more

GHRG, as the name implies, is a hormone which signals the release of Growth Hormone, but the Pituitary Gland can become less sensitive (i.e. release less GH). Melatonin can increase this sensitivity, ultimately resulting in a larger GH spike than would normally occur otherwise. read more

It has also been show that melatonin and resistance training alone increase the levels of growth hormone [4]. Erika Nassar et al. [5] decided to determine the effects of ingestion of a single dose of melatonin and heavy resistance exercise on serum growth hormone, somatostatin, and other hormones of the growth hormone/insulin-like growth factor 1 (IGF-1) axis. read more

Melatonin has some GABAergic activity. GABA + a hypoglycemic state are going to promote release of GH. IIRC. read more

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