Does protein synthesis take any energy (ATP)?

Ryan Nelson has written a good answer but I wanted to amplify it a little. Not only does protein synthesis “take any energy” — it amounts to 95% of the energy budget in an E. coli cell! That is a LOT. And a small protein of 100 amino acid residues uses up about 400 “~P” where “squiggle P” basically means ATP plus GTP. read more

Not only does protein synthesis “take any energy” — it amounts to 95% of the energy budget in an E. coli cell! That is a LOT. And a small protein of 100 amino acid residues uses up about 400 “~P” where “squiggle P” basically means ATP plus GTP. read more

The addition of an amino acid to a growing peptide chain requires two ATP molecules for amino acid activation and another two ATP for peptide bond formation and ribosome translation, plus additional costs of about another ATP, for error correction and the synthesis of sequences that are removed during protein maturation. read more

Generally no, protein synthesis in isolation is a passive process. But the whole business of moving products that are used in protein synthesis in and around the cell, through the cytoplasm and across cell and nuclear membranes likely uses ATP in many cases. read more