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Does THC inhibit and or block GABA receptors?

Best Answers

The opposite is true. Cannabis The sensations of slight euphoria, relaxation, and amplified auditory and visual perceptions produced by marijuana are due almost entirely to its effect on the cannabinoid receptors in the brain. read more

The cannabis removes this inhibition by the GABA neurons and hence activates the dopamine neurons. In chronic consumers of cannabis, the loss of CB1 receptors in the brain’s arteries reduces the flow of blood, and hence of glucose and oxygen, to the brain. The main results are attention deficits, memory loss, and impaired learning ability. read more

THC, for instance, binds to the CB1 receptors, which reduces the enzyme cAMP which results in less protein kinase A. This results in potassium and calcium channels that ends up reducing the amount of neurotransmitters being released. read more

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