Does the Chargaff rule apply for a double-stranded RNA?

RNA is found as a single-stranded molecule. Chargaff's rule states that DNA helices contain equal molar ratios of A to T and G to C. This is because DNA is found as a double-stranded helix in which A and T and G and C bases pair complementarily. read more

RNA is found as a single-stranded molecule. Chargaff's rule states that DNA helices contain equal molar ratios of A to T and G to C. This is because DNA is found as a double-stranded helix in which A and T and G and C bases pair complementarily. RNA only forms local helices meaning that it doesn't necessarily contain equal ratios. read more

Chargaff's rules state that DNA from any cell of all organisms should have a 1:1 ratio (base Pair Rule) of pyrimidine and purine bases and, more specifically, that the amount of guanine should be equal to cytosine and the amount of adenine should be equal to thymine. read more

Chargaff's Rule does not apply to viral single stranded DNA genomes, they are too small. It does apply to to large single strands of DNA-- to clarify Parity rule says that in DS DNA A=T and G=C. Parity rule 2 says that in single stranded DNA of eucaryotes A approximates T and G approximates C..it is observational of multiple experiments. read more