How can the venom of brown house spiders affect a human?

The Brown Recluse, despite being very abundant in the central and southern part of the US, also bites only rarely (most of the "Recluse bites" you hear about appear not to actually be spider bites at all, let alone Recluse bites), but Recluse venom can have medically significant effects. read more

One of few common spiders whose bites can have a seriously harmful effect on humans, the brown recluse has venom that contains a rare protein that can cause a blackened lesion at the site of a bite, or a much less common, but more dangerous, systemic reaction in humans. read more