How densely packed are proteins in cytoplasm?

The volume and mass of a typical protein are about 22,000Å^3[2] and 50,000g/mol[3] respectively (very rough estimates which obviously depend a lot on the specific protein). The total volume of all proteins works out to between 20-35% of the total volume of the cell. This depends a lot on the organism, cell type, and stage in the cell cycle. read more

Proteins are synthesized by Ribosomes in the cytoplasm. tRNA delivers the needed amino-acids into the crease of this 2-part rRNA based structure, which generally has a large and a small subunit. So far I have not seen anyone mention that there are slightly different sized ribosomes based on the type of critter we are dealing with, be it Prokaryote, or Eukaryote. read more

Margaret Gardel explains that it is more than a simple solution inside the cell, but is a complex, densely packed fluid with unique physical properties. read more