Alexander the Great defeated King Darius III and the Persian army in 330 B.C. Darius was subsequently assassinated by one of his own followers. Although Alexander retained the Persian system of government until his own death in 323 B.C. Darius’s defeat marked the end of the Achaemenid dynasty and the Persian Empire. read more
That said, the Empire did not, strictly speaking, end. Alexander reigned in Iran as Artaxerxes V, and adopted Persian ways and customs, although he was never Zoroastrian. When he died a few years later, the Iranian plateau, Mesopotamia, Syria and Anatolia passed to Seleucus I Nicator, who founded the Seleucid Empire. read more
Most of the credit of the rise of the Persian Empire was due to the first Achaemenid Emperor, Cyrus the Great. He founded Persia after he united the Medes and the Persians to build a great Empire. He came to power in 559 BC and thanks to his military and political genius ruled the largest empire in the ancient world. read more