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How do eukaryotic cells secrete proteins?

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Secretion in bacteria specifically refers to the translocation of fully translated protein molecules directly across the cytoplasmic membrane, either by SecYEG or Tat or by a highly specialized secretion system: read more here [1, 2]. read more

For most of these proteins, this will involve incorporation into transport vesicles which fuse with the Golgi to form/join the cis-Golgi reticulum – number 3. Proteins to be secreted then progress through the Golgi in acis to trans direction – number 4, slowly shedding membrane and luminal proteins via retrograde transport – number 5. read more

It becomes necessary to know the intracellular pathway taken by a newly synthesized protein before it reaches the eukaryotic cell surface (see also Protein targeting). 2.1. Intracellular Trafficking of Exported Protein . For the most part, eukaryotes do not secrete proteins directly across the plasma membrane. read more

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