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How does BCG work on bladder cancer?

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The body's immune system cells are attracted to the bladder and activated by BCG, which in turn affects the bladder cancer cells. ... read more

BCG was derived by growing M. bovis until it became less virulent, or weakened. The original intent of deriving BCG was as a vaccine for infection, not for therapy of Bladder Cancer. Therefore BCG is a living bacterium, although weakened from its parental bacterium. BCG does not use the Mycobacterium tuberculosis bacterium. read more

Bacillus Calmette-Guerin therapy: Bacillus Calmette-Guerin (BCG) is the main intravesical immunotherapy for treating early-stage bladder cancer. BCG is a germ that is related to the one that causes tuberculosis (TB), but it doesn’t usually cause serious disease. read more

BCG helps prevent the cancer from coming back in the bladder lining. It also reduces the risk of the cancer becoming invasive. Doctors usually advise it if you have high-risk bladder cancer or sometimes if you have an intermediate-risk bladder tumour. read more

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