How does cirrhosis of the liver lead to cancer?

Not every cirrhosis leads to cancer. The types that lead to cancer usually have underlying causes. Most notably viral causes. Some drugs or chemicals which can alter the genetic sequence of the liver cells can cause cancer. read more

If enough iron builds up in the liver, it can lead to cirrhosis and liver cancer. Heavy alcohol use. Alcohol abuse is a leading cause of cirrhosis in the United States, which in turn is linked with an increased risk of liver cancer. Obesity. Being obese (very overweight) increases the risk of developing liver cancer. read more

Primary liver cancer, which starts in the liver, accounts for about 2% of cancers in the U.S., but up to half of all cancers in some undeveloped countries. This is mainly due to the prevalence of hepatitis, caused by contagious viruses, that predisposes a person to liver cancer. read more