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How does Listeria monocytogenes attract a cells actin?

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Stages in the intracellular life-cycle of Listeria monocytogenes. (Center) Cartoon depicting entry, escape from a vacuole, actin nucleation, actin-based motility, and cell-to-cell spread. (Outside) Representative electron micrographs from which the cartoon was derived. LLO, PLCs, and ActA are all described in the text. read more

To understand this, you need to understand what Arp2/3 does to a growing Actin filament.It associates with a pre-existing Actin Filament and gets acrivated by Nucleation Promoter Factor i.e. NPF and causes branching of Actin Filament. read more

Listeria monocytogenes is the species of pathogenic bacteria that causes the infection listeriosis. It is a facultative anaerobic bacterium, capable of surviving in the presence or absence of oxygen. It can grow and reproduce inside the host's cells and is one of the most virulent foodborne pathogens, with 20 to 30% of food borne listeriosis infections in high-risk individuals may be fatal. read more

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