How does sunlight contribute to the development of melanoma?

Most of the gene changes commonly seen in melanoma cells are not inherited. They are more likely the result of damage caused by sunlight. In some people, such as those with xeroderma pigmentosum (XP), the skin cells are not as able to repair damaged DNA. read more

(2 points) UV light from the sun’s rays can cause a mutation of the second copy of tumor suppressor genes. 3. read more

The authors also discovered the underlying mechanism to explain why melanoma can also develop in areas never exposed to sunlight: Because melanocytes generally have a limited capacity to repair any DNA damage, they have a higher mutation frequency rate and are more susceptible to the development of melanoma -- even without the effects of the sun."Melanoma, the deadliest form of skin cancer, continues to increase at a rate of 3 percent a year," says Dr. Tang. read more

Over the years, scientists across the world are discussing over the magnifying issue of ozone depletion in the stratosphere, and tropospheric global climate change. read more

Sunlight is radiation, and radiation includes particles that damage everything. Leave anything out in the sun and you can see it deteriorate over time. read more

"Identifying the underlying causes of melanoma allows researchers to develop new ways to assess a person's risk of melanoma, prevent the disease and aid in the design of more effective treatments," said Dr. Tang, who is also a member of the NYU Cancer Institute. Sunlight in the form of UVA radiation causes oxygen in melanocytes to damage DNA. read more