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How does syphilis overwhelm the immune system?

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Manifestations of secondary syphilis usually occur within 3 months of initial infection and are sometimes quite subtle. A detailed description of .... Destructive effects are thought to depend upon the immune response of the fetus and include spontaneous abortion, stillbirth, and premature delivery. read more

According to the CDC, a person with syphilis has a two to five times greater risk of acquiring human immunodeficiency (ih-myoo-no-dih-FIH-shen-see) virus (HIV), the virus that causes acquired immunodeficiency syndrome (AIDS), an infection that weakens the immune system. read more

The treponema pallidum bacteria carries three molecules which can potentially invade different types of tissues inside the body, and remain undetectable to the immune system, due to their size and also due to the time the decease takes to develop. read more

Venereal syphilis can be considered a contest between the ability of T. pallidum to avoid immune recognition and the adeptness of the host's innate and adaptive immune responses to “track down” and eliminate the spirochetal pathogen. read more

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