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How functional are cancer cells?

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Examples of hyper-functional tumor cells are found among the “carcinoid tumors,” a sub-type of endocrine tumor, i.e. a tumor of hormone-producing cells. “There are 2 types of lung carcinoid tumors: typical and atypical. The difference is based on how a tumor processes and makes serotonin (5-HT). read more

Green tea polyphenols actually inhibit an enzyme required for cancer cell growth. In addition to inhibiting cancer cells from growing, Polyphenols (GTP), has been found to kill cancer cells without affecting the healthy ones . The amount of green tea intake necessary for anti-cancer effects has been suggested to be around 3 cups of tea a day (in cases such as early stage breast cancer). read more

Using a cell culture assay (in vitro apoptosis) for choosing cancer drugs is no different than a marker like estrogen receptor or CD20 or a gene expression pattern. They are all markers. One is a structural marker, the other is a functional marker. A cell culture assay is a "functional" biomarker. read more

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