How hot can human cells get before they stop functioning?

Cellular disruption will cause cell death long before the entire contents of cell stop functioning. Cellular disruption occurs at the level where protein denaturation occurs which for humans varies with location but in the human brain happens above 104 degrees fahrenheit. read more

Your core body temperature is rising, your natural thermoregulatory functions can’t do a damn thing to stop it, and your body tissues are suffering permanent damage as a result. Your one and only hope right now is for medical services to arrive and cool you with specialist equipment. read more

If some cells are scraped away the remaining cells divide to fill the gap and then stop once they contact each other (density-dependent inhibition). Contact with neighboring cells and the availability of nutrients, growth factors, and a substratum for attachment limit cell density to a single layer. read more