How many water molecules does an aquaporin transport?

I am very confused about the 12.5 molecules figure as well. It is possible that it's an average figure rather than a number of actual molecules transported, but how this average figure is calculated is not clear to me. read more

Aquaporin can transport water at the rate of 10^6 molecules per seconds. Aquaporin basically shuttles water molecules in a single file (like a line up of single molecules) through a mostly hydrophobic pore with a few key residues. read more

For many years, scientists assumed that water leaked through the cell membrane, and some water does. However, this did not explain how water could move so quickly through some cells. Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. read more

The high reabsorption is reflecting the high transport rate of the individual aquaporin proteins: each functional unit can transport on the order of one billion water molecules per second. In 2003 the Nobel Prize in chemistry was awarded to Professor Peter Agre for his discovery of the aquaporin water channel. read more