Adults with rheumatoid arthritis, osteoarthritis and ankylosing spondylitis only take 250 milligrams, 375 milligrams or 500 milligrams of naproxen tablets and oral suspension medications twice a day, once in the morning and once in the evening, according to Mayo Clinic. read more
Naproxen sodium: Immediate-release oral tablet. The typical dosage is 275 to 550 mg twice daily. The maximum dose is 1,650 mg per day. This should be given for a limited time period (up to 6 months). Extended-release oral tablet. The typical dosage is 750 or 1,000 mg once daily. The maximum dose is 1,500 mg per day. read more