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How much Ritalin would cause overdose/fatality?

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Curiosity, you said? If healthy and not suffering from cardiac issues, LD50 of methylphenidate is unbelievably high. So damn high, that your stomach would be filled with 10mg tabs and still won't do the job. read more

Note: Taking Ritalin on the regular basis will eventually bring you closer to death, since it causes neurotoxicity due the overexcitation of neurons (glutamate receports constantly on edge). Downregulation of dopamine and serotonin after you stop taking it can also promote suicidal tendencies. read more

Because Ritalin is reported to be highly addictive, the possibility of developing a tolerance to the drug is heightened. Tolerance to this medication will cause the user to have to take higher doses of the drug in order to produce the desired effect, which, in turn, could increase the risk of a potentially fatal Ritalin overdose. read more

Methylphenidate overdose symptoms can be very serious. A single overdose can result in permanent brain damage or death, particularly if a large amount of methylphenidate is ingested and treatment is delayed. read more

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