If you cut Deadpool in half vertically which side will heal?

It depends. Scenario One: If Deadpool were to be cut in half horizontally, the half containing the brain may regenerate, due to it controlling his nervous system (including regeneration, I presume). read more

During the Dark Reign storyline Deadpool has a cross over with the Thunderbolts which ends with his head being cut off. Everyone is left to believe that this act would leave him dead as he would not be able to regenerate from this. read more

We won’t really know until Deadpool 2 comes out. As some people mentioned, Laura and the other mutants that escape at the end of Logan could lead to a resurgence of the mutant population. It’s also possible that in the future there are no mutants. read more