It's hard to say if anime and manga is popular in the US on the same level in Japan. But I'll say this: anime and manga still remain a niche in the US. I believe in Japan, anime is not mainstream although manga in Japan is more accepted then anime (or so I've heard). read more
In Japan however, there are even names for different manga (comic) genres that target different age and gender groups: shounen (boys), shoujo (girls), seinen (men) and josei (women) and these manga cover a variety of genres including comedy, fantasy and drama. read more