Yes. It’s an NMDA-antagonist dissociative with strong and terribly unpredictable effects. It’s stimulant activity is likely a result of Dopamine Reuptake Inihibition although diphenidine and some of it’s relatives have affinities for sigma sites and a couple of other sites. The research done so far is scant (esp. where human use is concerned). read more
Purpose: Diphenidine is a potent synthetic dissociative anesthetic drug that has recently emerged in drug markets of Europe, Japan and America. The aim of this review is to summarize the current knowledge about this drug concerning its chemistry, synthesis, prevalence, pharmacology, toxicology and metabolism, as well as its legal status. read more
"Diphenidine is a novel dissociative anaesthetic drug with mild stimulant potential and a large amnestic component, making it relatively easy to feel like you black out during the experience, unable to recall what has happened. read more