Is it true that Chihuahua and Mastiffs dogs can't interbreed?

They can breed. In fact, believing that a little male dog can't impregnate a large female has resulted in several “surprise” litters. Where there is a will… a female in standing heat really wants to be bred and an intact male presented with a fema... read more

Bull Mastiff Chihuahua Mix. Satan's Mastiff. All members of the same species should be able to interbreed. Both of these “successful” matings between chihuahua males and Mastiff females were done by artificial insemination. So they are in a sense manufactured animals. I would want first to know if the resulting animals are healthy. read more

According to Joseph Janish, author of The Dogue de Bordeaux, these dogs are “very sensitive to anesthesia. A “normal” dose can be lethal.” He recommends that owners of DDB make sure that their veterinarian is familiar with the breed and their hypersensitivity. read more