nitrous oxide. A total of 170 drugs (1018 brand and generic names) are known to interact with nitrous oxide. Nitrous oxide is in the drug class general anesthetics. Valium. A total of 943 drugs (5823 brand and generic names) are known to interact with Valium. Valium is a member of the following drug classes: benzodiazepine anticonvulsants, benzodiazepines. read more