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How do amphetamines affect epilepsy?

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Amphetamine adds lots of EMG (muscle) artifact, which obscures the EEG and it tends to reduce the voltage in general. Any strong stimulant will have this effect. Drugs that increase beta are the benzodiazapines and barbiturates. read more

Amphetamines reduce seizure threshold (they make seizures more likely). They pose risks for people with epilepsy. read more

Amphetamines have been reported to cause seizures when combined with an antidepressant, such as sertraline.73 Amphetamines rarely cause seizures when used in therapeutic doses for treatment of attention deficit hyperactivity disorder, even in children with epilepsy. read more

Forty-four patients presenting with first-ever seizure within 24 h of illicit use of amphetamine or related analogs (amphetamine-associated seizures, AAS) were identified over 8 years. Patients with AAS were compared to control groups of other first-ever seizure patients (provoked n = 126 and unprovoked n = 401). read more

Using amphetamine improperly can cause death or serious side effects on the heart. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended. This medicine may be habit-forming. read more

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