Of the native American tribes, which were the most advanced?

: : I will obviate the usual suspects -Aztecs, Incans, Mayans- because the first was actually an hegemony of three different city-states, the second a full-fledged multi-ethnic empire, and the third is an ethnic identity shared by different polities & peoples along a period of almost four millennia. read more

If you're talking about Native American as it is understood in the USA it's a tough question to answer. The Mississippian Culture was a very advanced trade culture who lived in large settlement (often with several hundred if not thousands of people), as were many of the peoples from the Pacific Northwest. read more

The Great Plains Indians were the most advanced for its time. read more