Francine is an anthropomorphic monkey with a brown complexion. She has short brown hair, which she puts barrettes on to pin it up (her clips are red in the books, but yellow in the cartoon show). read more
Arthur Read - Arthur is one of Francine's best friends. Though they are best friends, Francine seems to always pick on Arthur, such as calling him a "four-eyes" when he first got glasses in Arthur's Eyes and a "baby" for not having lost a tooth in Arthur's Tooth. read more
The main supporting characters are D.W., Buster, Francine, Muffy, Binky, the Brain, Mr. Ratburn, and Arthur's parents. Over the years, the roles of each character have changed as more episodes focused on characters besides Arthur or D.W., most notably Buster, Francine, Muffy, Binky, and the Brain. read more