How cells use checkpoints at the end of G1 phase, end of G2 phase, and partway through M phase (the spindle checkpoint) to regulate the cell cycle. read more
Cell cycle checkpoints are control mechanisms in eukaryotic cells which ensure proper division of the cell. Each checkpoint serves as a potential point along the cell cycle, during which the conditions of the cell are assessed, with progression through the various phases of the cell cycle occurring when favorable conditions are met. read more
Section 13.7 Checkpoints in Cell-Cycle Regulation Catastrophic genetic damage can occur if cells progress to the next phase of the cell cycle before the previous phase is properly completed. For example, when S-phase cells are induced to enter mitosis by fusion to a cell in mitosis, the MPF present in the mitotic cell forces the chromosomes of the S-phase cell to condense. read more