Most CO2 is transported in the blood as hydrogencarbonates. Some CO2 reacts preferentially with deoxyhaemoglobin to form carbamates. Both of these reactions (dissolving and reacting) produce H+ ions that in turn raise the acidity of the blood. read more
When carbon dioxide binds to hemoglobin, carbaminohemoglobin is formed, lowering haemoglobin's affinity for oxygen via the Bohr effect. In the absence of oxygen, unbound hemoglobin molecules have a greater chance of becoming carbaminohaemoglobin. read more
The effect of carbon dioxide in the blood. Haemoglobin can also bind carbon dioxide, but to a lesser extent. Carbaminohaemoglobin forms. Some carbon dioxide is carried in this form to the lungs from respiring tissues. The presence of carbon dioxide helps the release of oxygen from haemoglobin, this is known as the Bohr effect. read more
Carbon dioxide affects the curve in two ways. First, CO 2 accumulation causes carbamino compounds to be generated through chemical interactions, which bind to hemoglobin forming carbaminohemoglobin. CO 2 is considered an Allosteric regulation as the inhibition happens not at the binding site of hemoglobin. read more