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What are the major causes of depression?

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Depression is a complex disease. WebMD explains what research has discovered about the causes of depression - from genetics to illnesses and medications to major life events. read more

Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest. Also called major depressive disorder or clinical depression, it affects how you feel, think and behave and can lead to a variety of emotional and physical problems. read more

Major depressive disorder is a mood disorder that interferes with daily life. Learn about symptoms, causes, and treatment. Major depressive disorder is a mood disorder that interferes with daily life. read more

Depression is not simply the result of a ‘chemical imbalance’, for example because you have too much or not enough of a particular brain chemical. It’s complicated, and there are multiple causes of major depression. read more

There are a number of factors that may increase the chance of depression, including the following: Abuse. Past physical, sexual, or emotional abuse can cause depression later in life. Certain medications. For example, some drugs used to treat high blood pressure, such as beta-blockers or reserpine, can increase your risk of depression. Conflict. read more

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