What are the mechanisms of action behind lead poisoning?

Lead is a ubiquitous environmental toxin that is capable of causing numerous acute and chronic circulatory, neurological, hematological, gastrointestinal, reproductive and immunological pathologies. The mechanism of lead induced toxicity is not fully understood. read more

In the US in the 20th century, there were two major peaks in use of lead, one was in the 1910's and 20's as lead paint was increasingly used, the other was in 50's, 60's and 70's, when leaded gasoline became increasingly common. read more

Lead poisoning results in various different health problems including hypertension, coronary artery disease, peripheral artery disease and stroke, although the underlying mechanisms involved are not fully understood. read more