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What are the metabolic changes of atherosclerosis?

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Arteries have a relatively small lumen, meaning that the pressure of the blood, and subsequent risk of developing atherosclerosis, is higher in these vessels. Arteries have strong thick walls with lots of collagen (a fibrous protein) that give them extra strength to withstand the high pressure of the blood. read more

We investigated 40 minipigs known to develop human-like atherosclerosis spontaneously and assessed the metabolic effects of a high fat + fructose diet (HFF) fed for 30 weeks. The pigs were part of a study investigating the effects of MLDL1278A, a human antibody against oxidized apolipoprotein B . read more

Metabolic changes in the arterial wall associated with atherosclerosis in the pigeon. St Clair RW. White Carneau (WC) pigeons are susceptible to both naturally occurring and cholesterol-aggravated aortic atherosclerosis whereas Show Racers (SR) are resistant. read more

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