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What are the similarities between stem cells and cancer cells?

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Semin Cancer Biol. 2010 Apr;20(2):85-92. doi: 10.1016/j.semcancer.2010.04.002. Epub 2010 Apr 29. Normal stem cells and cancer stem cells: similar and different. Shackleton M(1). read more

With this theory, cancer cells that are not stem cells can cause problems, but cannot sustain an attack on the bodies over a long period of time. It should be noted, however, due to many studies being unsuccessful in discovering the similarities and differences between normal tissue stem cells and cancer stem cells, there is some debate on whether or not cancer stem cells actually exist. read more

Since 2007, cell biologists have been able to induce specialized, differentiated cells (such as those obtained from the skin or muscle of a human adult) to become iPSCs. Like embryonic stem cells, iPSCs are a type of stem cell that is able to become any cell type. read more

"This suggests that such cancer cell reprogramming could become a new way of treating cancer patients, in essence telling their tumors to turn into normal stem cells." Knoepfler said the team is continuing to study the differences and similarities between iPSCs and cancer cells, as well as investigate possible ways to make iPSCs safer. read more

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