What are YAC and BAC vectors?

Bacterial artificial chromosome vectors (BACs) were developed to permit the cloning and stable maintenance of large (100–200 kb) pieces of DNA in E. coli. .... read more

The key difference between YAC and BAC is that YAC is an artificially constructed vector system using a specific region of yeast chromosome to insert large segments of genetic materials to yeast cells while BAC is an artificially constructed vector system using a specific region of E. coli chromosome to insert large segments of DNA into E. coli cells. read more

YAC vectors The realization that the components of a eukaryotic chromosome that are required for stable replication and segregation, at least in the yeast Saccharomyces cerevisiae, consist of rather small and well-defined sequences has led to the construction of recombinant chromosomes (yeast artificial chromosomes; YACs). read more

YAC and BAC are artificial chromosomes developed in order to clone large genomic DNA fragments. They have multiple purposes which include making genomic libraries and cDNA libraries. read more