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What causes kidney disease and renal failure?

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Chronic kidney disease — Learn about kidney failure symptoms, tests, diagnosis and treatment options, including medication, dialysis and kidney transplant. read more

Chronic intrinsic kidney failure. This happens when there is long-term damage to the kidneys due to intrinsic kidney disease. Intrinsic kidney disease is caused by a direct trauma to the kidneys, such as severe bleeding or a lack of oxygen. Chronic post-renal kidney failure. A long-term blockage of the urinary tract prevents urination. This causes pressure and eventual kidney damage. read more

Occasionally, acute kidney failure causes permanent loss of kidney function, or end-stage renal disease. People with end-stage renal disease require either permanent dialysis — a mechanical filtration process used to remove toxins and wastes from the body — or a kidney transplant to survive. Death. read more

Post renal causes of kidney failure (post=after + renal= kidney) are due to factors that affect outflow of the urine: Obstruction of the bladder or the ureters can cause back-pressure because the kidneys continue to produce urine, but the obstruction acts like a dam, and urine backs up into the kidneys. read more

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