One of the functions of the enzyme in animals is to interconvert carbon dioxide and bicarbonate to maintain acid-base balance in blood and other tissues, and to help transport carbon dioxide out of tissues. read more
Inherited deficiency of pyrimidine 5′ nucleotidase is the third most common enzymatic deficiency resulting in hemolysis. Pyrimidine 5′ nucleotidase participates in RNA degradation in reticulocytes. The accumulation of pyrimidines in the red cells is presumed to be toxic and a cause of hemolysis. read more