What is Hypersplenism anemia?

Other symptoms may be present that reflect the underlying disease that has caused hypersplenism. An enlarged spleen can be caused by a variety of diseases, including hemolytic anemia, liver cirrhosis, leukemia, malignant lymphoma and other infections and inflammatory diseases. read more

Some of the underlying causes of hypersplenism or enlarged spleen can be prevented, such as certain forms of anemia and cirrhosis of the liver due to alcohol. In other cases, the hypersplenism may not be preventable, as it is a complication to an underlying disorder. read more

Splenomegaly is usually associated with increased workload (such as in hemolytic anemias), which suggests that it is a response to hyperfunction. It is therefore not surprising that splenomegaly is associated with any disease process that involves abnormal red blood cells being destroyed in the spleen. read more

In some cases, your doctor may recommend radiation to shrink your spleen. In one study, low-dose radiation reduced the size of the spleen in 78 percent of participants and improved anemia in another 75 percent. In severe cases of hypersplenism, removal of the spleen (called a splenectomy) may be necessary. read more